The time domain is the emerging forefront of astronomical research with newfacilities and instruments providing unprecedented amounts of data on thetemporal behavior of astrophysical populations. Dealing with the size andcomplexity of this requires new techniques and methodologies. Quasars are anideal work set for developing and applying these: they vary in a detectable butnot easily quantifiable manner whose physical origins are poorly understood. Inthis paper, we will review how quasars are identified by their variability andhow these techniques can be improved, what physical insights into theirvariability can be gained from studying extreme examples of variability, andwhat approaches can be taken to increase the number of quasars known. Thesewill demonstrate how astroinformatics is essential to discovering andunderstanding this important population.
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